The leading human rights organization for all individuals with Down syndrome.

National Down Syndrome Society
8 E 41st Street, 8th Floor
New York New York 10017
[email protected] 


Featured ImageThrough a variety of research programs and activities, now focusing on advocacy for Down syndrome research on the federal level, NDSS has long played a major role in advancing knowledge about Down syndrome.

  1. Research & Down Syndrome

    Since 1979, the National Down Syndrome Society has been at the forefront of Down syndrome research.

  2. DS-Connect™: The Down Syndrome Registry

    NDSS is excited to be a part of DS-Connect™: The Down Syndrome Registry, the Down syndrome registry hosted by the National Institutes of Health and the Down Syndrome Consortium.

  3. Guide to Clinical Trials & Research Studies for People with Down Syndrome & Their Families

    Use this guide to learn about how trials and studies are structured and the kinds of questions you might ask when considering participating in a research study or clinical trial.

  4. Directory of Current Studies

    A listing of clinical trials and research studies actively recruiting participants with Down syndrome.

  • Buddy Walk
  • NDSS Yourway
  • NDSS DS-Ambassadors