General Donations

Your donation allows us to continue the important work we do to promote the value, acceptance and inclusion of people with Down syndrome. Thank you for supporting the NDSS mission!



Online donations to NDSS are easy and secure.

Click here to donate online.


By Phone

Please call the toll-free NDSS helpline at 800-221-4602, Monday – Friday, 9am-5pm ET to make a donation by phone.

Call the toll-free helpline.

By Phone

By Mail or Fax

Please download the donation form and enclose with your donation. Mail or fax the completed form to:

National Down Syndrome Society
8 E 41st Street, 8th Floor
New York, NY 10017
Fax: 646-870-9320

By Mail or Fax

Please note, the National Down Syndrome Society is a registered 501(c)(3) nonprofit organization. All donations of $250 or more will receive a letter of acknowledgment for tax purposes. For donations under $250, your cancelled check or credit card statement serve as your receipt.

Other Ways to Give

Recurring Monthly Donations
Honor Tribute
Memorial Tribute
Stock Donations
Planned Giving
NDSS Your Way (Peer-to-peer Fundraising)
Corporate Matching

We Respect Your Privacy

The National Down Syndrome Society (NDSS) is committed to respecting the privacy of its financial and in-kind donors, whether the donation is made online, by mail, or any other method. When you make a financial or in-kind donation, you provide your name and contact information. Financial donors provide standard payment information including, in many circumstances, credit card data. We protect your information in a variety of ways, as described below.

We use industry standard safeguards to protect your information. Many donors use credit cards for donations. We protect the security of credit card transactions using a number of measures such as encryption, access controls, network firewalls, and physical security. These measures make it extremely difficult for anyone to intercept the credit card information you send to us. When we work with other companies to process credit card transactions, those companies also use encryption and other appropriate security measures.

We will not sell, share or trade our donors’ personally identifiable information with any other entity.