The leading human rights organization for all individuals with Down syndrome.

National Down Syndrome Society
8 E 41st Street, 8th Floor
New York New York 10017
[email protected] 


800-221-4602 /[email protected]

Through our toll-free helpline and email service, NDSS receives more than 10,000 requests a year for information on Down syndrome.  NDSS responds to questions from parents, professionals, self-advocates and other interested individuals.

An NDSS Information & Referral Specialist is available to respond to email inquiries and phone calls between the hours of 9am and 5pm ET, Monday - Friday. The helpline is also supported by a translation service that can be accessed in over 150 languages.

NDSS resources

  • Printed Materials
    NDSS publishes new and expectant parent guides, guidebooks about aging and Down syndrome and informational brochures in English and Spanish. 
  • Buddy Walk
  • NDSS Yourway
  • NDSS DS-Ambassadors